2. Chronic atrophic gastritis - Low Power
In normal gastric mucosa, the glands lie in a back-to-back
configuration. In this atrophic mucosa, there is a loss of gastric
glands. In atrophic gastritis, intestinal metaplasia is often seen,
characterized by the formation of intestinal type epithelium with
goblet cells. which can be stained pink using a mucin stain. The
mucin in the goblet cells stains pink when stained with a mucicarmine
stain, which does not stain gastric-type epithelial cells. Patients
with extensive atrophic gastritis are more likely to develop
dysplasia, characterized by closely packed hyperchromatic,
pseudo-stratified nuclei.
